| 09. Apr | TuRu Düsseldorf | - | SSVg Velbert 02 | 3 | : | 1 |
| Cronenberger SC | - | FC Kray | 2 | : | 3 | |
| Ratinger Spvg. Germania 04/19 | - | SV Hönnepel-Niedermörmter | 3 | : | 0 | |
| KFC Uerdingen | - | VfB Homberg | 1 | : | 0 | |
| VfB 03 Hilden | - | SC Düsseldorf-West | 3 | : | 2 | |
| VfR Krefeld-Fischeln | - | TSV Meerbusch | 4 | : | 1 | |
| ETB Schwarz-Weiss Essen | - | TV Jahn Dinslaken-Hiesfeld | 4 | : | 0 | |
| Spvg Schonnebeck 1910 | - | 1.FC Bocholt | 0 | : | 3 | |
| SC 1911 Kapellen-Erft | - | Sportfreunde Baumberg | 1 | : | 0 |
| 09. Apr | FC BW Friesdorf | - | Hilal-Maroc Bergheim | 5 | : | 4 |
| TSV Germania Windeck | - | TSC Euskirchen | 0 | : | 4 | |
| FC Hürth | - | TV Herkenrath 09 | 1 | : | 3 | |
| FC Hennef 05 | - | Viktoria Arnoldsweiler | 2 | : | 1 | |
| SV Bergisch Gladbach 09 | - | FC Inde Hahn | 4 | : | 0 | |
| Borussia Freialdenhoven | - | Vfl Alfter | 1 | : | 1 | |
| Siegburger SV 04 | - | SpVg. Wesseling-Urfeld | 5 | : | 2 | |
| Vfl Rheinbach | - | FC Wegberg-Beeck | 2 | : | 2 |
| 08. Apr | FSC Lohfelden 1924 | - | 1.FC Viktoria 07 Kelsterbach | 3 | : | 0 |
| TSV Lehnerz | - | FC Bayern Alzenau | 0 | : | 2 | |
| SV Rot-Weiss Hadamar | - | FC Viktoria 09 Urberach | 2 | : | 0 | |
| Sportfreunde Seligenstadt | - | SC Hessen Dreieich | 4 | : | 0 | |
| KSV Baunatal | - | SG Rot-Weiß Frankfurt | 1 | : | 3 | |
| SC Borussia Fulda | - | Eintracht Stadtallendorf | 1 | : | 2 | |
| OSC Velmar | - | SV Steinbach | 2 | : | 4 | |
| SC Viktoria Griesheim | - | FC Ederbergland | 1 | : | 1 |
| 07. Apr | FC St. Pauli II | - | Hannover 96 II | 0 | : | 0 |
| SpVgg. Drochtersen/Assel | - | Hamburger SV II | 4 | : | 0 | |
| VfB Lübeck | - | SV Eichede | 1 | : | 0 | |
| 08. Apr | VfL Wolfsburg II | - | VfB Oldenburg | 4 | : | 2 |
| BSV Schwarz-Weiß Rehden | - | ETSV Weiche Flensburg | 0 | : | 2 | |
| SV Meppen | - | FC Eintracht Norderstedt | 3 | : | 0 | |
| 09. Apr | 1.FC Germania Egestorf-Langreder | - | U.L.M. Wolfsburg | 2 | : | 1 |
| Lüneburger SK Hansa | - | TSV Havelse | 0 | : | 1 | |
| 10. Apr | VfV Borussia 06 Hildesheim | - | Eintracht Braunschweig II | 0 | : | 3 |
| 07. Apr | 18:30 | 1.FC Nürnberg | - | FC St.Pauli | 0 | : | 2 |
| SV Sandhausen | - | DSC Arminia Bielefeld | 1 | : | 3 | ||
| FC Kickers Würzburg | - | Hannover 96 | 0 | : | 0 | ||
| 08. Apr | 13:00 | 1.FC Kaiserslautern | - | SpVgg. Greuther Fürth | 2 | : | 0 |
| 1.FC Heidenheim 1846 | - | VfL Bochum 1848 | 0 | : | 0 | ||
| 09. Apr | 13:30 | FC Erzgebirge Aue | - | TSV 1860 München | 3 | : | 0 |
| Fortuna Düsseldorf | - | 1.FC Union Berlin | 2 | : | 2 | ||
| VfB Stuttgart | - | Karlsruher SC | 2 | : | 0 | ||
| 10. Apr | 20:15 | Eintracht Braunschweig | - | SG Dynamo Dresden | 1 | : | 0 |
| 07. Apr | 20:30 | Eintracht Frankfurt | - | SV Werder Bremen | 2 | : | 2 |
| 08. Apr | 15:30 | RB Leipzig | - | Bayer Leverkusen | 1 | : | 0 |
| 1.FC Köln | - | Borussia Mönchengladbach | 2 | : | 3 | ||
| SC Freiburg | - | 1.FSV Mainz 05 | 1 | : | 0 | ||
| FC Schalke 04 | - | Vfl Wolfsburg | 4 | : | 1 | ||
| Hamburger SV | - | TSG 1899 Hoffenheim | 2 | : | 1 | ||
| 18:30 | FCB München | - | Borussia Dortmund | 4 | : | 1 | |
| 09. Apr | 15:30 | Hertha BSC Berlin | - | FC Augsburg | 2 | : | 0 |
| 17:30 | FC Ingolstadt 04 | - | SV Darmstadt 98 | 3 | : | 2 |
| 08. Apr | 14:00 | FSV Zwickau | - | VfR Aalen | 2 | : | 1 |
| SV Werder Bremen II | - | Chemnitzer FC | 0 | : | 0 | ||
| SV Wehen Wiesbaden | - | FC Rot-Weiß Erfurt | 0 | : | 0 | ||
| SC Fortuna Köln | - | VfL Sportfreunde Lotte | 3 | : | 0 | ||
| SC Paderborn 07 | - | FSV Frankfurt 1899 | 3 | : | 0 | ||
| VfL Osnabrück | - | Hallescher FC | 1 | : | 2 | ||
| MSV Duisburg | - | SG Sonnenhof Großaspach | 2 | : | 1 | ||
| 09. Apr | 14:00 | Holstein Kiel | - | SC Preußen Münster | 0 | : | 0 |
| 1.FSV Mainz 05 II | - | FC Hansa Rostock | 2 | : | 4 | ||
| 1.FC Magdeburg | - | SSV Jahn Regensburg | 1 | : | 2 |
| 07. Apr | SV Babelsberg 03 | - | Berliner AK 07 | 1 | : | 0 |
| BFC Dynamo | - | RB Leipzig II | 1 | : | 6 | |
| VfB Auerbach | - | FC Oberlausitz Neugersdorf | 1 | : | 1 | |
| 09. Apr | FSV Budissa Bautzen | - | FSV Wacker Nordhausen | 0 | : | 1 |
| FC Carl Zeiss Jena | - | FSV 63 Luckenwalde | 3 | : | 0 | |
| FC Viktoria 1889 Berlin | - | FC Schönberg 95 | 4 | : | 0 | |
| TSG Neustrelitz | - | Hertha BSC Berlin II | 1 | : | 2 | |
| FSV Union Fürstenwalde | - | FC Energie Cottbus | 1 | : | 1 | |
| ZFC Meuselwitz | - | 1.FC Lokomotive Leipzig | 2 | : | 1 |
| 08. Apr | SC Rot-Weiß Oberhausen | - | SC Wiedenbrück 2000 | 3 | : | 1 |
| TSG 1881 Sprockhövel | - | Borussia Mönchengladbach II | 1 | : | 3 | |
| SG Wattenscheid 09 | - | Bonner SC 01/04 | 3 | : | 0 | |
| SC Verl 1924 | - | Rot Weiss Ahlen | 0 | : | 2 | |
| Alemannia Aachen | - | SV Rödinghausen 1970 | 4 | : | 1 | |
| 1.FC Köln II | - | FC Viktoria Köln 1904 | 2 | : | 0 | |
| Sportfreunde Siegen 1899 | - | Wuppertaler SV | 1 | : | 0 | |
| Borussia Dortmund II | - | Rot-Weiss Essen | 1 | : | 1 | |
| 09. Apr | FC Schalke 04 II | - | Fortuna Düsseldorf II | 4 | : | 0 |
| 07. Apr | FC Nöttingen | - | TSG 1899 Hoffenheim II | 3 | : | 4 |
| FK Pirmasens | - | SV Eintracht Trier 05 | 3 | : | 0 | |
| SSV Ulm 1846 | - | KSV Hessen Kassel | 1 | : | 2 | |
| VfB Stuttgart II | - | 1.FC Kaiserslautern II | 2 | : | 2 | |
| 08. Apr | TuS Koblenz | - | TSV Steinbach | 2 | : | 1 |
| VfR Wormatia Worms | - | SV 07 Elversberg | 0 | : | 0 | |
| FC Astoria Walldorf | - | SV Waldhof Mannheim | 3 | : | 3 | |
| 09. Apr | 1.FC Saarbrücken | - | Stuttgarter Kickers | 3 | : | 1 |
| Kickers Offenbach | - | FC 08 Homburg | 4 | : | 0 |
| 07. Apr | TSV Buchbach | - | SV Wacker Burghausen | 3 | : | 1 |
| FC Memmingen | - | FC Bayern München II | 1 | : | 1 | |
| 08. Apr | SpVgg. Unterhaching | - | SV Seligenporten | 1 | : | 1 |
| VfR Garching | - | FC Augsburg II | 0 | : | 0 | |
| FC Ingolstadt 04 II | - | FV Illertissen | 1 | : | 0 | |
| TSV 1860 Rosenheim | - | SV Schalding-Heining | 3 | : | 0 | |
| TSV 1860 München II | - | 1. FC Schweinfurt 05 | 1 | : | 1 | |
| 09. Apr | SpVgg Greuther Fürth II | - | SpVgg. Bayern Hof | 4 | : | 3 |
| 25. Apr | SpVgg Oberfranken Bayreuth | - | 1. FC Nürnberg II | 1 | : | 4 |
| 04. Apr | 20:00 | Borussia Dortmund | - | Hamburger SV | 3 | : | 0 |
| 1.FC Köln | - | Eintracht Frankfurt | 1 | : | 0 | ||
| TSG 1899 Hoffenheim | - | FCB München | 1 | : | 0 | ||
| SV Werder Bremen | - | FC Schalke 04 | 3 | : | 0 | ||
| 05. Apr | 20:00 | Borussia Mönchengladbach | - | Hertha BSC Berlin | 1 | : | 0 |
| SV Darmstadt 98 | - | Bayer Leverkusen | 0 | : | 2 | ||
| FC Augsburg | - | FC Ingolstadt 04 | 2 | : | 3 | ||
| Vfl Wolfsburg | - | SC Freiburg | 0 | : | 1 | ||
| 1.FSV Mainz 05 | - | RB Leipzig | 2 | : | 3 |
| 04. Apr | 19:00 | VfR Aalen | - | SC Fortuna Köln | 3 | : | 0 |
| FC Rot-Weiß Erfurt | - | SV Werder Bremen II | 1 | : | 1 | ||
| SSV Jahn Regensburg | - | 1.FSV Mainz 05 II | 2 | : | 1 | ||
| 20:30 | Chemnitzer FC | - | 1.FC Magdeburg | 1 | : | 1 | |
| 05. Apr | 18:00 | FSV Frankfurt 1899 | - | FSV Zwickau | 0 | : | 1 |
| 19:00 | Hallescher FC | - | SC Paderborn 07 | 1 | : | 1 | |
| SC Preußen Münster | - | VfL Sportfreunde Lotte | 1 | : | 0 | ||
| Holstein Kiel | - | SV Wehen Wiesbaden | 3 | : | 0 | ||
| FC Hansa Rostock | - | MSV Duisburg | 1 | : | 0 | ||
| SG Sonnenhof Großaspach | - | VfL Osnabrück | 1 | : | 0 |
| 04. Apr | 17:30 | FC St.Pauli | - | SV Sandhausen | 0 | : | 0 |
| Hannover 96 | - | 1.FC Nürnberg | 1 | : | 0 | ||
| DSC Arminia Bielefeld | - | Fortuna Düsseldorf | 2 | : | 1 | ||
| Karlsruher SC | - | FC Kickers Würzburg | 1 | : | 1 | ||
| 05. Apr | 17:30 | TSV 1860 München | - | VfB Stuttgart | 1 | : | 1 |
| SG Dynamo Dresden | - | 1.FC Heidenheim 1846 | 2 | : | 1 | ||
| SpVgg. Greuther Fürth | - | Eintracht Braunschweig | 0 | : | 0 | ||
| 1.FC Union Berlin | - | FC Erzgebirge Aue | 0 | : | 1 | ||
| VfL Bochum 1848 | - | 1.FC Kaiserslautern | 0 | : | 0 |
| 31. Mrz | SV Seligenporten | - | TSV Buchbach | 0 | : | 2 |
| FC Bayern München II | - | VfR Garching | 2 | : | 1 | |
| 01. Apr | FC Augsburg II | - | TSV 1860 Rosenheim | 4 | : | 1 |
| SV Schalding-Heining | - | TSV 1860 München II | 1 | : | 3 | |
| SpVgg Greuther Fürth II | - | FC Memmingen | 0 | : | 1 | |
| FV Illertissen | - | SpVgg. Unterhaching | 3 | : | 3 | |
| SpVgg. Bayern Hof | - | SV Wacker Burghausen | 0 | : | 1 | |
| 1. FC Nürnberg II | - | FC Ingolstadt 04 II | 0 | : | 6 | |
| 03. Apr | 1. FC Schweinfurt 05 | - | SpVgg Oberfranken Bayreuth | 2 | : | 0 |
| 31. Mrz | GD Chaves | - | Paços de Ferreira | 1 | : | 0 |
| CD Nacional | - | Vitória Guimarães | 1 | : | 2 | |
| 01. Apr | CD Tondela | - | GD Estoril | 0 | : | 2 |
| Boavista | - | Rio Ave FC | 0 | : | 1 | |
| SL Benfica | - | FC Porto | 1 | : | 1 | |
| 02. Apr | Vitória Setúbal | - | Moreirense FC | 2 | : | 0 |
| Os Belenenses | - | CD Feirense | 1 | : | 2 | |
| FC Arouca | - | Sporting CP | 1 | : | 2 | |
| Sporting Braga | - | CS Marítimo | 3 | : | 3 |
| 02. Apr | SV Fortuna Hagen III | - | KSV Croatia Hagen | 4 | : | 2 |
| RSV Selbecke | - | SG Vorhalle 09 II | 0 | : | 8 | |
| SV Hohenlimburg IV | - | Hagen United | 4 | : | 3 |
| 02. Apr | RSV Selbecke II | - | FC Herdecke-Ende IV | 3 | : | 3 |
| SG Boelerheide II | - | SpVg. Hagen 1911 IV | 0 | : | 3 | |
| Kickers Hagen | - | SC Berchum/Garenfeld IV | 1 | : | 3 |
