| 12. Apr | GD Chaves | - | Os Belenenses | 2 | : | 2 |
| 13. Apr | CD Santa Clara | - | Moreirense FC | 1 | : | 1 |
| Portimonense SC | - | FC Porto | 0 | : | 3 | |
| CD Aves | - | Sporting CP | 1 | : | 3 | |
| 14. Apr | Rio Ave FC | - | Vitória Guimarães | 2 | : | 1 |
| CS Marítimo Funchal | - | CD Feirense | 2 | : | 0 | |
| Boavista Porto | - | CD Nacional Funchal | 1 | : | 0 | |
| Sporting Braga | - | CD Tondela | 3 | : | 0 | |
| SL Benfica | - | Vitória Setúbal | 4 | : | 2 |
| 12. Apr | FCO Dijon | - | Amien SC | 0 | : | 0 |
| FC Nantes | - | Olympique Lyon | 2 | : | 1 | |
| 13. Apr | Olympique de Marseille | - | Olympique Nîmes | 2 | : | 1 |
| SM Caen | - | Angers SCO | 0 | : | 1 | |
| AS Monaco | - | Stade Reims | 0 | : | 0 | |
| Racing Straßburg | - | EA Guingkamp | 3 | : | 3 | |
| 14. Apr | HSC Montpellier | - | Toulouse FC | 2 | : | 1 |
| Stade Rennes | - | OGC Nizza | 0 | : | 0 | |
| AS St.Ètienne | - | Girondins Bordeaux | 3 | : | 0 | |
| OSC Lille | - | Paris St.Germain | 5 | : | 1 |
| 09. Apr | FC Liverpool | - | FC Porto | 2 | : | 0 | |
| 17. Apr | FC Porto | - | FC Liverpool | 1 | : | 4 | |
| FC Liverpool | - | FC Porto | 6 | : | 1 | ||
| 09. Apr | Tottenham Hotspur | - | Manchester City FC | 1 | : | 0 | |
| 17. Apr | Manchester City FC | - | Tottenham Hotspur | 4 | : | 3 | |
| Tottenham Hotspur | - | Manchester City FC | 4 | : | 4 | ||
| 10. Apr | Ajax Amsterdam | - | Juventus Turin | 1 | : | 1 | |
| 16. Apr | Juventus Turin | - | Ajax Amsterdam | 1 | : | 2 | |
| Ajax Amsterdam | - | Juventus Turin | 3 | : | 2 | ||
| 10. Apr | Manchester United | - | FC Barcelona | 0 | : | 1 | |
| 16. Apr | FC Barcelona | - | Manchester United | 3 | : | 0 | |
| Manchester United | - | FC Barcelona | 0 | : | 4 | ||
| 14. Apr | SC Concordia Hagen II | - | Hiddinghauser FV II | 2 | : | 2 |
| TSV Fichte Hagen II | - | SG BW Haspe | 5 | : | 2 | |
| SSV Hagen II | - | FC Bosna Hagen | 1 | : | 1 | |
| FC Polonia Hagen | - | SG Boelerheide | 2 | : | 2 | |
| RSV Selbecke | - | SG Vorhalle 09 | 2 | : | 4 | |
| SpVg. Hagen 1911 IV | - | TSV Dahl | 3 | : | 5 |
| 14. Apr | VfB Schwelm II | - | FSV Gevelsberg III | 1 | : | 3 |
| FC SW Silschede II | - | RSV Altenvoerde | 2 | : | 2 | |
| SuS Volmarstein II | - | SC Obersprockhövel III | 4 | : | 2 | |
| TuS Esborn II | - | FC Wetter 10/30 II | 2 | : | 2 | |
| SV Büttenberg | - | BW Voerde II | 1 | : | 6 |
| 14. Apr | FC Iliria Hagen II | - | TSV Dahl II | 3 | : | 2 |
| FC Hellas/Makedonikos Hagen II | - | SV Boele-Kabel II | 1 | : | 2 | |
| Blau-Weiß Vorhalle | - | SG Boelerheide II | 14 | : | 0 | |
| RSV Selbecke II | - | SG Vorhalle 09 II | 0 | : | 5 | |
| KSV Croatia Hagen | - | TSV Hagen 1860 | 6 | : | 1 | |
| TSV Fichte Hagen III | - | Hagen United | 7 | : | 0 | |
| Al Seddiq Hagen II | - | Hasper SV II | 5 | : | 4 |
| 14. Apr | SuS Volmarstein III | - | Hagen United | 6 | : | 3 | |
| SC Berchum/Garenfeld IV | - | SG BW Haspe II | 9 | : | 1 | W | |
| Roter Stern Wehringhausen | - | SC Wengern 5813 II | 3 | : | 0 | ||
| TSG Fussball Herdecke II | - | TuS Hasslingshausen II | 2 | : | 2 | ||
| TuS Esborn III | - | SC Zurstraße 70 II | 1 | : | 1 |
| 14. Apr | FC Gevelsberg-Vogelsang II | - | SC Zurstraße 1970 | 2 | : | 10 |
| SpVg. SW Breckerfeld II | - | SV Ararat Gevelsberg II | 9 | : | 0 | |
| SV Büttenberg II | - | SpVg. Linderhausen II | 1 | : | 2 | |
| Sportfreunde Haspe II | - | RSV Altenvoerde II | 5 | : | 1 | |
| SG Vatanspor Gevelsberg | - | BW Voerde III | 5 | : | 3 |
| 12. Apr | 18:30 | 1.FC Union Berlin | - | SSV Jahn Regensburg | 2 | : | 2 |
| FC Erzgebirge Aue | - | 1.FC Heidenheim 1846 | 0 | : | 1 | ||
| 13. Apr | 13:00 | SV Sandhausen | - | SG Dynamo Dresden | 3 | : | 1 |
| SC Paderborn 07 | - | MSV Duisburg | 4 | : | 0 | ||
| 1.FC Magdeburg | - | SV Darmstadt 98 | 0 | : | 1 | ||
| 14. Apr | 13:30 | VfL Bochum 1848 | - | SpVgg. Greuther Fürth | 3 | : | 2 |
| FC Ingolstadt 04 | - | Holstein Kiel | 1 | : | 1 | ||
| FC St.Pauli | - | DSC Arminia Bielefeld | 1 | : | 1 | ||
| 15. Apr | 20:30 | 1.FC Köln | - | Hamburger SV | 1 | : | 1 |
| 12. Apr | 19:00 | SV Meppen | - | Hallescher FC | 0 | : | 2 |
| 13. Apr | 14:00 | FC Energie Cottbus | - | 1.FC Kaiserslautern | 1 | : | 1 |
| TSV 1860 München | - | SC Preußen Münster | 0 | : | 1 | ||
| Eintracht Braunschweig | - | SG Sonnenhof Großaspach | 1 | : | 1 | ||
| VfR Aalen | - | VfL Sportfreunde Lotte | 1 | : | 2 | ||
| FC Hansa Rostock | - | FC Carl Zeiss Jena | 1 | : | 2 | ||
| SV Wehen Wiesbaden | - | SC Fortuna Köln | 3 | : | 0 | ||
| 14. Apr | 13:00 | SpVgg. Unterhaching | - | FSV Zwickau | 0 | : | 1 |
| 14:00 | Krefelder FC Uerdingen 05 | - | VfL Osnabrück | 1 | : | 3 | |
| 15. Apr | 19:00 | FC Kickers Würzburg | - | Karlsruher SC | 0 | : | 0 |
| 12. Apr | FC Ingolstadt 04 II | - | TSV Buchbach | 3 | : | 2 |
| 13. Apr | SV Wacker Burghausen | - | SV Heimstetten | 3 | : | 2 |
| FC Pipinsried | - | FC Augsburg II | 0 | : | 3 | |
| VfB Eichstätt | - | FC Memmingen | 2 | : | 1 | |
| FV Illertissen | - | SV Viktoria Aschaffenburg | 2 | : | 3 | |
| SV Schalding-Heining | - | VfR Garching | 5 | : | 2 | |
| 1. FC Nürnberg II | - | SpVgg Oberfranken Bayreuth | 2 | : | 2 | |
| SpVgg Greuther Fürth II | - | 1. FC Schweinfurt 05 | 0 | : | 2 | |
| 15. Apr | Bayern München II | - | TSV 1860 Rosenheim | 1 | : | 1 |
| 13. Apr | FC Schalke 04 II | - | TuS Erndtebrück | 7 | : | 0 |
| 14. Apr | ASC 09 Dortmund | - | FC Gütersloh | 2 | : | 1 |
| TuS Haltern | - | TSG Sprockhövel | 1 | : | 0 | |
| TuS Ennepetal | - | FC Brünninghausen | 3 | : | 2 | |
| 1.FC Gievenbeck | - | Hammer SpVg. | 0 | : | 5 | |
| SV Westfalia Rhynern | - | Rot Weiss Ahlen | 1 | : | 1 | |
| FC Eintracht Rheine | - | Sportfreunde Siegen | 1 | : | 1 | |
| SC Paderborn 07 II | - | SV Schermbeck 1912 | 3 | : | 1 | |
| SC Westfalia Herne | - | Holzwickeder SC | 2 | : | 0 |
| 13. Apr | SC Viktoria Griesheim | - | KSV Hessen Kassel | 0 | : | 3 |
| SV Rot-Weiss Hadamar | - | SC Waldgirmes | 3 | : | 1 | |
| FSC Lohfelden 1924 | - | Hünfelder SV | 2 | : | 0 | |
| FC Gießen | - | FC Eddersheim | 2 | : | 3 | |
| KSV Baunatal | - | FC Ederbergland | 3 | : | 2 | |
| FV Bad Vilbel | - | SV Buchonia Flieden | 2 | : | 0 | |
| 14. Apr | Türk Gücu Friedberg | - | SG Barockstadt Fulda-Lehnerz | 1 | : | 4 |
| VfB Ginsheim | - | SpVgg. Neu-Isenburg | 4 | : | 2 |
| 12. Apr | FC Wegberg-Beeck | - | SV Deutz 05 | 4 | : | 0 |
| 14. Apr | VfL Alfter | - | Siegburger SV 04 | 1 | : | 1 |
| FC Hürth | - | Borussia Freialdenhoven | 1 | : | 1 | |
| Viktoria Arnoldsweiler | - | SV Breinig | 2 | : | 0 | |
| FC Hennef 05 | - | SSV Merten | 4 | : | 0 | |
| FC Blau-Weiß Friesdorf | - | Spvg. Frechen 20 | 3 | : | 1 | |
| VfL Vichttal | - | SV Bergisch Gladbach 09 | 0 | : | 4 |
| 13. Apr | TV Jahn Dinslaken Hiesfeld | - | 1.FC Bocholt | 1 | : | 2 |
| TSV Meerbusch | - | Sportfreunde Baumberg | 2 | : | 3 | |
| FSV Duisburg | - | SC Düsseldorf-West | 1 | : | 2 | |
| 14. Apr | Spvg Schonnebeck 1910 | - | SC Union Nettetal | 1 | : | 2 |
| VfB 03 Hilden | - | SC Velbert | 1 | : | 0 | |
| TuRU Düsseldorf | - | VfB Speldorf | 1 | : | 0 | |
| 1.FC Kleve 63/03 | - | Ratinger Spvg. Germania 04/19 | 0 | : | 1 | |
| SSVg Velbert 02 | - | ETB Schwarz-Weiss Essen | 1 | : | 1 | |
| 1.FC Monheim | - | VfB Homberg | 1 | : | 1 |
| 12. Apr | Delbrücker SC | - | SV Borussia Emsdetten | 1 | : | 4 |
| 14. Apr | SV Rödinghausen II | - | SV Mesum | 1 | : | 2 |
| TSV Victoria Clarholz | - | SpVg. Beckum | 0 | : | 0 | |
| SpVgg. Vreden | - | SC Herford | 2 | : | 0 | |
| SC Rot Weiss Maaslingen | - | SC Preußen Münster II | 1 | : | 3 | |
| VfL Theesen | - | SC Roland 1962 Beckum | 1 | : | 0 | |
| TuS Hiltrup | - | SuS Neuenkirchen | 1 | : | 0 |
| 14. Apr | BV Westfalia Wickede | - | DSC Wanne-Eickel | 0 | : | 1 |
| SC Neheim | - | SpVgg. Erkenschwick | 2 | : | 1 | |
| DJK TuS Hordel | - | Kirchhörder SC | 4 | : | 0 | |
| Lüner SV | - | Concordia Wiemelhausen | 3 | : | 1 | |
| BSV Schüren | - | TuS 05 Sinsen | 2 | : | 3 | |
| RSV Meinerzhagen | - | YEG Hassel | 6 | : | 0 | |
| FC Lennestadt | - | FC Iserlohn | 4 | : | 2 |
| 14. Apr | FSV Gerlingen | - | BSV Menden | 2 | : | 1 |
| SV Brilon | - | FSV Werdohl | 2 | : | 0 | |
| Rot-Weiß Hünsborn | - | VSV Wenden | 4 | : | 0 | |
| TuS Erndtebrück II | - | SV Hüsten | 4 | : | 0 | |
| SSV Hagen | - | SV Rot-Weiß Erlinghausen | 1 | : | 3 | |
| SpVg. Olpe | - | VfL Bad Berleburg | 1 | : | 1 | |
| FC Borussia Dröschede | - | SV Hohenlimburg 1910 | 1 | : | 0 |
