| 21. Jan | Galatasaray | - | Dinamo Kiev | 3 | : | 3 | |
| 22. Jan | Beşiktaş | - | Athletic Bilbao | 4 | : | 1 | |
| 23. Jan | FC Porto | - | Olympiakos Piraeus | 0 | : | 1 | |
| Fenerbahçe | - | Olympique Lyonnais | 0 | : | 0 | ||
| AZ Alkmaar | - | AS Roma | 1 | : | 0 | ||
| Malmö FF | - | FC Twente | 2 | : | 3 | ||
| Qarabağ FK | - | FCSB | 2 | : | 3 | ||
| FK Bodø / Glimt | - | Maccabi Tel Aviv | 3 | : | 1 | ||
| Viktoria Plzeň | - | RSC Anderlecht | 2 | : | 0 | ||
| TSG 1899 Hoffenheim | - | Tottenham Hotspur | 2 | : | 3 | ||
| Eintracht Frankfurt | - | Ferencvárosi TC | 2 | : | 0 | ||
| Manchester United | - | Rangers FC | 2 | : | 1 | ||
| Lazio Roma | - | Real Sociedad | 3 | : | 1 | ||
| PAOK Saloniki | - | Slavia Praha | 2 | : | 0 | ||
| Union Saint-Gilloise | - | Sporting Braga | 2 | : | 1 | ||
| PFC Ludogorets Razgrad | - | FC Midjylland | 0 | : | 2 | ||
| IF Elfsborg | - | OGC Nice | 1 | : | 0 | ||
| Rigas Futbola skola (FK RFS) | - | AFC Ajax | 1 | : | 0 | ||