| 25. Sep | AZ Alkmaar | - | IF Elfsborg | 3 | : | 2 | |
| FK Bodø/Glimt | - | FC Porto | 3 | : | 2 | ||
| Manchester United | - | FC Twente | 1 | : | 1 | ||
| PFC Ludogorets Razgrad | - | Slavia Praha | 0 | : | 2 | ||
| Galatasaray | - | PAOK Saloniki | 3 | : | 1 | ||
| Dinamo Kiev | - | Lazio Roma | 0 | : | 3 | ||
| FC Midjylland | - | TSG 1899 Hoffenheim | 1 | : | 1 | ||
| RSC Anderlecht | - | Ferencvárosi TC | 2 | : | 1 | ||
| OGC Nice | - | Real Sociedad | 1 | : | 1 | ||
| 26. Sep | Fenerbahçe | - | Union Saint-Gilloise | 2 | : | 1 | |
| Malmö FF | - | Rangers FC | 0 | : | 2 | ||
| AS Roma | - | Athletic Bilbao | 1 | : | 1 | ||
| Eintracht Frankfurt | - | Viktoria Plzeň | 3 | : | 3 | ||
| Tottenham Hotspur | - | Qarabağ FK | 3 | : | 0 | ||
| AFC Ajax | - | Beşiktaş | 4 | : | 0 | ||
| Sporting Braga | - | Maccabi Tel Aviv | 2 | : | 1 | ||
| Olympique Lyonnais | - | Olympiakos Piraeus | 2 | : | 0 | ||
| FCSB | - | Rigas Futbola skola | 4 | : | 1 | ||